MK-2866 (Ostarine) | Advanced SARM & Muscle
$75.00
MK-2866, also known as Ostarine or Enobosarm, is one of the most extensively studied Selective Androgen Receptor Modulators (SARMs) in the scientific community. Originally developed to treat conditions such as muscle wasting and osteoporosis, MK-2866 is investigated for its ability to bind selectively to androgen receptors in muscle and bone tissue. It is a primary subject for researchers focusing on increasing lean body mass and improving physical function without the significant virilization or prostatic issues associated with traditional anabolic steroids.
MK-2866: The Science of Selective Androgen Agonism
The Biochemistry of MK-2866
MK-2866 is a non-steroidal SARM that demonstrates a high degree of tissue selectivity. It acts as a full agonist in skeletal muscle and bone, while exhibiting minimal activity in secondary androgenic tissues like the prostate or sebaceous glands. Its chemical structure allows for high oral bioavailability and a stable half-life, making it a reliable compound for consistent laboratory modeling.
Mechanism of Action: Targeted Anabolic Signaling
In advanced musculoskeletal and endocrine research, MK-2866 functions through several coordinated physiological pathways:
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Androgen Receptor Selection: The compound binds to the androgen receptor with high affinity, triggering the recruitment of co-activators that initiate the transcription of muscle-building genes.
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Protein Synthesis Upregulation: Research focuses on the compound’s ability to increase the rate of protein synthesis, facilitating the repair and growth of skeletal muscle fibers.
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Bone Mineral Density Support: MK-2866 is investigated for its capacity to stimulate osteoblastic activity and decrease osteoclastic resorption, potentially strengthening bone architecture.
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Lipid Metabolism Modulation: Studies observe that selective androgen signaling may improve insulin sensitivity and support the reduction of adipose tissue in metabolic research models.
Primary Research Applications
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Cancer Cachexia and Wasting: Analyzing the prevention of muscle loss in models of chronic illness or age-related sarcopenia.
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Osteoporosis Research: Investigating the stabilization of bone mineral density and the prevention of fractures in estrogen-deficient or aging models.
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Surgical Recovery Modeling: Studying the potential for MK-2866 to accelerate tissue healing and the restoration of physical strength following orthopedic procedures.
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Pelvic Floor Health: Emerging research focuses on the compound’s effect on the integrity of pelvic floor muscles in models of stress urinary incontinence.
4. Technical Specifications (E-E-A-T Data)
| Feature | Scientific Specification |
| Chemical Name | ((2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide) |
| Molecular Formula | $C_{19}H_{14}F_{3}N_{3}O_{3}$ |
| Molecular Weight | 389.33 g/mol |
| CAS Number | 841205-47-8 |
| Purity Grade | $\geq$99% (HPLC Verified) |
| Form | Research Grade Tablets (10mg Standardized) |
| Solubility | Soluble in DMSO, Ethanol, and Propylene Glycol |
5. Product FAQ
Q: Is MK-2866 the same as Ostarine?
A: Yes. MK-2866 is the research code name for the compound widely known as Ostarine or Enobosarm.
Q: Does MK-2866 suppress natural hormones?
A: In research models, MK-2866 has shown a dose-dependent effect on the hypothalamic-pituitary-gonadal (HPG) axis. While generally less suppressive than anabolic steroids, researchers monitor for changes in LH, FSH, and endogenous testosterone during long-term studies.
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