Andarine S4 | Advanced SARM & Lean Mass
$76.00
Andarine S4 (Acetamidoxolutamide) is an orally active, non-steroidal Selective Androgen Receptor Modulator (SARM) characterized by its high affinity for androgen receptors in skeletal muscle and bone tissue. Developed for the treatment of conditions such as muscle wasting and osteoporosis, Andarine S4 is a foundational compound in pharmacological research. It is investigated for its ability to promote lean mass accrual and increase strength while demonstrating a reduced impact on secondary androgenic organs compared to traditional androgens.
Andarine S4: The Science of High-Affinity Androgen Signaling
The Biochemistry of Andarine S4
Andarine S4 is a partial agonist of the androgen receptor (AR). Its chemical structure allows it to bind specifically to ARs in the musculoskeletal system, where it initiates the transcription of genes responsible for protein synthesis. Unlike earlier generations of androgens, Andarine S4 was engineered to minimize the risk of prostatic enlargement and other systemic androgenic side effects by exhibiting lower activity in non-target tissues.
Mechanism of Action: Targeted Anabolic Modulation
In advanced musculoskeletal and metabolic research, Andarine S4 functions through several coordinated physiological pathways:
-
Selective Androgen Binding: The compound binds to the AR with high potency, facilitating the repair and growth of skeletal muscle fibers.
-
Lean Mass Preservation: Research focuses on the compound’s ability to prevent muscle catabolism, particularly in models of calorie restriction or chronic wasting.
-
Fat Oxidation and Lipolysis: Andarine S4 is investigated for its potential to support the reduction of adipose tissue by increasing metabolic demand and prioritizing lipid use for energy.
-
Bone Mineralization: Studies observe that AR activation by Andarine S4 can stimulate osteoblast activity, contributing to the study of bone density stabilization.
Primary Research Applications
-
Sarcopenia and Cachexia Modeling: Analyzing the maintenance of lean tissue in models of age-related or disease-induced muscle loss.
-
Osteoporosis Research: Investigating the impact of selective androgen signaling on bone turnover and fracture resistance.
-
Adipose Tissue Regulation: Studying the relationship between AR agonism and the modulation of body composition in metabolic research.
-
Strength and Physical Function: Observing the impact of S4 on motor performance and physical endurance in laboratory models.
4. Technical Specifications (E-E-A-T Data)
| Feature | Scientific Specification |
| Chemical Name | (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide |
| Molecular Formula | $C_{19}H_{18}F_{3}N_{3}O_{6}$ |
| Molecular Weight | 441.36 g/mol |
| CAS Number | 401900-40-1 |
| Purity Grade | $\geq$99% (HPLC Verified) |
| Form | Research Grade Tablets (25mg Standardized) |
| Solubility | Soluble in DMSO and Ethanol |
5. Product FAQ
Q: Is Andarine S4 a steroid?
A: No. Andarine S4 is a Selective Androgen Receptor Modulator (SARM). While it targets the same receptors as steroids, its non-steroidal structure allows it to target muscle and bone tissue with greater specificity.
Q: Why is Andarine S4 researched for body composition?
A: Andarine S4 is investigated for its dual ability to stimulate muscle protein synthesis while potentially supporting fat oxidation, making it a primary subject for studies on metabolic health and lean mass preservation.
Related products
NEUROPEPTIDE RESEARCH COMPOUNDS
GROWTH HORMONE RESEARCH PEPTIDES
RESEARCH-GRADE COMPOUNDS
RESEARCH-GRADE COMPOUNDS
BPC-157 | Advanced Tissue Repair & Gastric Research Compound
GLP-1 & METABOLIC RESEARCH COMPOUNDS
NEUROPEPTIDE RESEARCH COMPOUNDS
